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Human DYRK2 (aa 1-601 )
DYRK2 Swiss Prot#
Q92630
DYRK2 Protein names
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
DYRK2 Gene names
DYRK2
Organism
Human
DYRK2 Entry name
DYRK2_HUMAN
DYRK2 Codon optimized cDNA Clone
DYRK2 CDNA Cat#
RPC0477
cDNA Tag
cDNA DYRK2 Contains A 6x histidine tag
Condon optimized DYRK2 CDNA Formulation
Liquid
Condon optimized DYRK2 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized DYRK2 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant DYRK2 Protein
Recombinant DYRK2 Protein Cat#
PC0477
DYRK2 Protein Source
Recombinant protein.
Recombinant DYRK2 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant DYRK2 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant DYRK2 Protein Activity
N/A
Recombinant protein Tag
Recombinant DYRK2 contains A 6x histidine tag
Recombinant DYRK2 Protein Formulation
Liquid
Recombinant DYRK2 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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DYRK2 Protein family
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK

subfamily
DYRK2 Subcellular locations
Cytoplasm. Nucleus.
DYRK2 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Role in the regulation of cellular growth and/or development.

Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in

response to DNA damage, functioning downstream of ATM. Inactivates

GYS1 by phosphorylation at Ser-641, and potential
DYRK2 Sequence databases
EMBL DDBJ GenBank
DYRK2 3D structure databases
ModBase
DYRK2 Protein-protein interaction databases
STRING
DYRK2 Proteomic databases
PRIDE
DYRK2 Genome annotation databases
Ensembl GeneID KEGG UCSC
DYRK2 Organism specific databases
CTD MGI
DYRK2 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
DYRK2 Gene expression databases
Bgee ArrayExpress Genevestigator
DYRK2 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY