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Human Zinc finger protein ZIC 2 (a.a.1-532)
ZIC2 Swiss Prot#
O95409
ZIC2 Protein names
Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2)
ZIC2 Gene names
ZIC2
Organism
Human
ZIC2 Entry name
ZIC2_HUMAN
ZIC2 Codon optimized cDNA Clone
ZIC2 CDNA Cat#
RPS1024
cDNA Tag
cDNA ZIC2 Contains A 6x histidine tag
Condon optimized ZIC2 CDNA Formulation
Liquid
Condon optimized ZIC2 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized ZIC2 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant ZIC2 Protein
Recombinant ZIC2 Protein Cat#
PS1024
ZIC2 Protein Source
Recombinant protein.
Recombinant ZIC2 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant ZIC2 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant ZIC2 Protein Activity
N/A
Recombinant protein Tag
Recombinant ZIC2 contains A 6x histidine tag
Recombinant ZIC2 Protein Formulation
Liquid
Recombinant ZIC2 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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ZIC2 Protein family
GLI C2H2-type zinc-finger protein family
ZIC2 Subcellular locations
Nucleus. Cytoplasm.
ZIC2 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Acts as a transcriptional activator or repressor. Plays

important roles in the early stage of organogenesis of the CNS. Activates

the transcription of the serotonin transporter SERT in uncrossed ipsilateral

retinal ganglion cells (iRGCs) to refine eye-specific projections in primary

visual targets. Its transcriptional activity is repressed by MDFIC. Involved

in the formation of the ipsilateral retinal projection at the optic chiasm

midline. Drives the expression of EPHB1 on ipsilaterally projecting growth

cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'.

Associates to the basal SERT promoter region from ventrotemporal retinal

segments of retinal embryos.
ZIC2 Sequence databases
EMBL DDBJ GenBank
ZIC2 3D structure databases
ModBase
ZIC2 Protein-protein interaction databases
STRING
ZIC2 Proteomic databases
PRIDE
ZIC2 Genome annotation databases
Ensembl GeneID KEGG UCSC
ZIC2 Organism specific databases
CTD MGI
ZIC2 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
ZIC2 Gene expression databases
Bgee ArrayExpress Genevestigator
ZIC2 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY