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Human Zinc finger protein DPF3 (a.a.1-378)
DPF3 Swiss Prot#
Q92784
DPF3 Protein names
Zinc finger protein DPF3 (Zinc finger protein cer-d4) (BRG1-associated

factor 45C) (BAF45C)
DPF3 Gene names
DPF3 BAF45C CERD4
Organism
Human
DPF3 Entry name
DPF3_HUMAN
DPF3 Codon optimized cDNA Clone
DPF3 CDNA Cat#
RPS0155
cDNA Tag
cDNA DPF3 Contains A 6x histidine tag
Condon optimized DPF3 CDNA Formulation
Liquid
Condon optimized DPF3 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized DPF3 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant DPF3 Protein
Recombinant DPF3 Protein Cat#
PS0155
DPF3 Protein Source
Recombinant protein.
Recombinant DPF3 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant DPF3 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant DPF3 Protein Activity
N/A
Recombinant protein Tag
Recombinant DPF3 contains A 6x histidine tag
Recombinant DPF3 Protein Formulation
Liquid
Recombinant DPF3 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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DPF3 Protein family
Requiem/DPF family
DPF3 Subcellular locations
Nucleus.
DPF3 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Belongs to the neuron-specific chromatin remodeling complex

(nBAF complex). During neural development a switch from a

stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs

as neurons exit the cell cycle and become committed to their adult state. The

transition from proliferating neural stem/progenitor cells to post-mitotic

neurons requires a switch in subunit composition of the npBAF and nBAF

complexes. As neural progenitors exit mitosis and differentiate into

neurons, npBAF complexes which contain ACTL6A/BAF53A and

PHF10/BAF45A, are exchanged for homologous alternative

ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-

specific complexes (nBAF). The npBAF complex is essential for the self-

renewal/proliferative capacity of the multipotent neural stem cells. The nBAF

complex along with CREST plays a role regulating the activity of genes

essential for dendrite growth (By similarity). Muscle-specific component of

the BAF complex, a multiprotein complex involved in transcriptional

activation and repression of select genes by chromatin remodeling

(alteration of DNA-nucleosome topology). Specifically binds acetylated

lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac,

H4K16ac). In the complex, it acts as a tissue-specific anchor between

histone acetylations and methylations and chromatin remodeling. It thereby

probably plays an essential role in heart and skeletal muscle development.
DPF3 Sequence databases
EMBL DDBJ GenBank
DPF3 3D structure databases
ModBase
DPF3 Protein-protein interaction databases
STRING
DPF3 Proteomic databases
PRIDE
DPF3 Genome annotation databases
Ensembl GeneID KEGG UCSC
DPF3 Organism specific databases
CTD MGI
DPF3 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
DPF3 Gene expression databases
Bgee ArrayExpress Genevestigator
DPF3 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY