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Human Interferon-induced, double-stranded RNA protein kinase (a.a.1-551)
EIF2AK2 Swiss Prot#
P19525
EIF2AK2 Protein names
Interferon-induced, double-stranded RNA protein kinase (EC

2.7.11.1) (Interferon-inducible RNA-dependent protein kinase) (Eukaryotic

translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2)

(Protein kinase RNA) (PKR) (
EIF2AK2 Gene names
EIF2AK2 PKR PRKR
Organism
Human
EIF2AK2 Entry name
E2AK2_HUMAN
EIF2AK2 Codon optimized cDNA Clone
EIF2AK2 CDNA Cat#
RPS0175
cDNA Tag
cDNA EIF2AK2 Contains A 6x histidine tag
Condon optimized EIF2AK2 CDNA Formulation
Liquid
Condon optimized EIF2AK2 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized EIF2AK2 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant EIF2AK2 Protein
Recombinant EIF2AK2 Protein Cat#
PS0175
EIF2AK2 Protein Source
Recombinant protein.
Recombinant EIF2AK2 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant EIF2AK2 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant EIF2AK2 Protein Activity
N/A
Recombinant protein Tag
Recombinant EIF2AK2 contains A 6x histidine tag
Recombinant EIF2AK2 Protein Formulation
Liquid
Recombinant EIF2AK2 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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EIF2AK2 Protein family
Protein kinase superfamily, Ser/Thr protein kinase family, GCN2 subfamily
EIF2AK2 Subcellular locations
-
EIF2AK2 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Following activation by double-stranded RNA in the presence of

ATP, the kinase becomes autophosphorylated and can catalyze the

phosphorylation of the translation initiation factor EIF2S1, which leads to an

inhibition of the initiation of protein synthesis. Double-stranded RNA is

generated during the course of a viral infection.
EIF2AK2 Sequence databases
EMBL DDBJ GenBank
EIF2AK2 3D structure databases
ModBase
EIF2AK2 Protein-protein interaction databases
STRING
EIF2AK2 Proteomic databases
PRIDE
EIF2AK2 Genome annotation databases
Ensembl GeneID KEGG UCSC
EIF2AK2 Organism specific databases
CTD MGI
EIF2AK2 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
EIF2AK2 Gene expression databases
Bgee ArrayExpress Genevestigator
EIF2AK2 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY