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Human ETS-related transcription factor Elf-3 (a.a.1-371)

ELF3 Swiss Prot#

P78545

ELF3 Protein names

ETS-related transcription factor Elf-3 (E74-like factor 3) (Epithelium-specific

Ets transcription factor 1) (ESE-1) (Epithelium-restricted Ets protein ESX)

(Epithelial-restricted with serine box)

ELF3 Gene names

ELF3 ERT ESX JEN

Organism

Human

ELF3 Entry name

ELF3_HUMAN

ELF3 Codon optimized cDNA Clone

ELF3 CDNA Cat#

RPS0178

cDNA Tag

cDNA ELF3 Contains A 6x histidine tag

Condon optimized ELF3 CDNA Formulation

Liquid

Condon optimized ELF3 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized ELF3 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant ELF3 Protein

Recombinant ELF3 Protein Cat#

PS0178

ELF3 Protein Source

Recombinant protein.

Recombinant ELF3 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant ELF3 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant ELF3 Protein Activity

N/A

Recombinant protein Tag

Recombinant ELF3 contains A 6x histidine tag

Recombinant ELF3 Protein Formulation

Liquid

Recombinant ELF3 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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ELF3 Protein family

ETS family

ELF3 Subcellular locations

Cytoplasm. Nucleus.

ELF3 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Transcriptional activator that binds and transactivates ETS

sequences containing the consensus nucleotide core sequence GGA[AT].

Acts synergistically with POU2F3 to transactivate the SPRR2A promoter

and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates

collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2

and TGM3 promoters. Represses KRT4 promoter activity. Involved in

mediating vascular inflammation. May play an important role in epithelial

cell differentiation and tumorigenesis. May be a critical downstream effector

of the ERBB2 signaling pathway. May be associated with mammary gland

development and involution. Plays an important role in the regulation of

transcription with TATA-less promoters in preimplantation embryos, which is

essential in preimplantation development (By similarity).

ELF3 Sequence databases

EMBL

DDBJ

GenBank

ELF3 3D structure databases

ModBase

ELF3 Protein-protein interaction databases

STRING

ELF3 Proteomic databases

PRIDE

ELF3 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

ELF3 Organism specific databases

CTD

MGI

ELF3 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ELF3 Gene expression databases

Bgee

ArrayExpress

Genevestigator

ELF3 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY