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Human Interferon regulatory factor 2 (a.a.1-349)
IRF2 Swiss Prot#
P14316
IRF2 Protein names
Interferon regulatory factor 2 (IRF-2)
IRF2 Gene names
IRF2
Organism
Human
IRF2 Entry name
IRF2_HUMAN
IRF2 Codon optimized cDNA Clone
IRF2 CDNA Cat#
RPS0382
cDNA Tag
cDNA IRF2 Contains A 6x histidine tag
Condon optimized IRF2 CDNA Formulation
Liquid
Condon optimized IRF2 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized IRF2 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant IRF2 Protein
Recombinant IRF2 Protein Cat#
PS0382
IRF2 Protein Source
Recombinant protein.
Recombinant IRF2 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant IRF2 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant IRF2 Protein Activity
N/A
Recombinant protein Tag
Recombinant IRF2 contains A 6x histidine tag
Recombinant IRF2 Protein Formulation
Liquid
Recombinant IRF2 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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IRF2 Protein family
IRF family
IRF2 Subcellular locations
Nucleus.
IRF2 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Specifically binds to the upstream regulatory region of type I IFN

and IFN-inducible MHC class I genes (the interferon consensus sequence

(ICS)) and represses those genes. Also acts as an activator for several

genes including H4 and IL7. Constitutively binds to the ISRE promoter to

activate IL7. Involved in cell cycle regulation through binding the site II

(HiNF-M) promoter region of H4 and activating transcription during cell

growth. Antagonizes IRF1 transcriptional activation.
IRF2 Sequence databases
EMBL DDBJ GenBank
IRF2 3D structure databases
ModBase
IRF2 Protein-protein interaction databases
STRING
IRF2 Proteomic databases
PRIDE
IRF2 Genome annotation databases
Ensembl GeneID KEGG UCSC
IRF2 Organism specific databases
CTD MGI
IRF2 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
IRF2 Gene expression databases
Bgee ArrayExpress Genevestigator
IRF2 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY