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Human Interferon regulatory factor 9 (a.a.1-393)
IRF9 Swiss Prot#
Q00978
IRF9 Protein names
Interferon regulatory factor 9 (IRF-9) (Transcriptional regulator ISGF3 subunit

gamma) (IFN-alpha-responsive transcription factor subunit) (Interferon-

stimulated gene factor 3 gamma) (ISGF-3 gamma) (ISGF3 p48 subunit)
IRF9 Gene names
IRF9 ISGF3G
Organism
Human
IRF9 Entry name
IRF9_HUMAN
IRF9 Codon optimized cDNA Clone
IRF9 CDNA Cat#
RPS0389
cDNA Tag
cDNA IRF9 Contains A 6x histidine tag
Condon optimized IRF9 CDNA Formulation
Liquid
Condon optimized IRF9 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized IRF9 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant IRF9 Protein
Recombinant IRF9 Protein Cat#
PS0389
IRF9 Protein Source
Recombinant protein.
Recombinant IRF9 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant IRF9 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant IRF9 Protein Activity
N/A
Recombinant protein Tag
Recombinant IRF9 contains A 6x histidine tag
Recombinant IRF9 Protein Formulation
Liquid
Recombinant IRF9 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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IRF9 Protein family
IRF family
IRF9 Subcellular locations
Cytoplasm. Nucleus.
IRF9 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Transcription regulatory factor that mediates signaling by type I

IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface

receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine

phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize,

associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription

factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response

element (ISRE) to activate the transcription of interferon stimulated genes,

which drive the cell in an antiviral state.
IRF9 Sequence databases
EMBL DDBJ GenBank
IRF9 3D structure databases
ModBase
IRF9 Protein-protein interaction databases
STRING
IRF9 Proteomic databases
PRIDE
IRF9 Genome annotation databases
Ensembl GeneID KEGG UCSC
IRF9 Organism specific databases
CTD MGI
IRF9 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
IRF9 Gene expression databases
Bgee ArrayExpress Genevestigator
IRF9 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY