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Human Mediator of RNA polymerase II transcription subunit 21 (a.a.1-144)
MED21 Swiss Prot#
Q13503
MED21 Protein names
Mediator of RNA polymerase II transcription subunit 21 (Mediator complex

subunit 21) (RNA polymerase II holoenzyme component SRB7) (RNAPII

complex component SRB7) (hSrb7)
MED21 Gene names
MED21 SRB7 SURB7
Organism
Human
MED21 Entry name
MED21_HUMAN
MED21 Codon optimized cDNA Clone
MED21 CDNA Cat#
RPS0481
cDNA Tag
cDNA MED21 Contains A 6x histidine tag
Condon optimized MED21 CDNA Formulation
Liquid
Condon optimized MED21 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized MED21 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant MED21 Protein
Recombinant MED21 Protein Cat#
PS0481
MED21 Protein Source
Recombinant protein.
Recombinant MED21 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant MED21 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant MED21 Protein Activity
N/A
Recombinant protein Tag
Recombinant MED21 contains A 6x histidine tag
Recombinant MED21 Protein Formulation
Liquid
Recombinant MED21 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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MED21 Protein family
Mediator complex subunit 21 family
MED21 Subcellular locations
Nucleus.
MED21 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Component of the Mediator complex, a coactivator involved in

the regulated transcription of nearly all RNA polymerase II-dependent genes.

Mediator functions as a bridge to convey information from gene-specific

regulatory proteins to the basal RNA polymerase II transcription machinery.

Mediator is recruited to promoters by direct interactions with regulatory

proteins and serves as a scaffold for the assembly of a functional

preinitiation complex with RNA polymerase II and the general transcription

factors.
MED21 Sequence databases
EMBL DDBJ GenBank
MED21 3D structure databases
ModBase
MED21 Protein-protein interaction databases
STRING
MED21 Proteomic databases
PRIDE
MED21 Genome annotation databases
Ensembl GeneID KEGG UCSC
MED21 Organism specific databases
CTD MGI
MED21 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
MED21 Gene expression databases
Bgee ArrayExpress Genevestigator
MED21 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY