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Human Mediator of RNA polymerase II transcription subunit 6 (a.a.1-246)
MED6 Swiss Prot#
O75586
MED6 Protein names
Mediator of RNA polymerase II transcription subunit 6 (Mediator complex

subunit 6) (hMed6) (Activator-recruited cofactor 33 kDa component) (ARC33)

(Renal carcinoma antigen NY-REN-28)
MED6 Gene names
MED6 ARC33
Organism
Human
MED6 Entry name
MED6_HUMAN
MED6 Codon optimized cDNA Clone
MED6 CDNA Cat#
RPS0486
cDNA Tag
cDNA MED6 Contains A 6x histidine tag
Condon optimized MED6 CDNA Formulation
Liquid
Condon optimized MED6 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized MED6 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant MED6 Protein
Recombinant MED6 Protein Cat#
PS0486
MED6 Protein Source
Recombinant protein.
Recombinant MED6 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant MED6 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant MED6 Protein Activity
N/A
Recombinant protein Tag
Recombinant MED6 contains A 6x histidine tag
Recombinant MED6 Protein Formulation
Liquid
Recombinant MED6 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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MED6 Protein family
Mediator complex subunit 6 family
MED6 Subcellular locations
Nucleus.
MED6 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Component of the Mediator complex, a coactivator involved in

the regulated transcription of nearly all RNA polymerase II-dependent genes.

Mediator functions as a bridge to convey information from gene-specific

regulatory proteins to the basal RNA polymerase II transcription machinery.

Mediator is recruited to promoters by direct interactions with regulatory

proteins and serves as a scaffold for the assembly of a functional

preinitiation complex with RNA polymerase II and the general transcription

factors.
MED6 Sequence databases
EMBL DDBJ GenBank
MED6 3D structure databases
ModBase
MED6 Protein-protein interaction databases
STRING
MED6 Proteomic databases
PRIDE
MED6 Genome annotation databases
Ensembl GeneID KEGG UCSC
MED6 Organism specific databases
CTD MGI
MED6 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
MED6 Gene expression databases
Bgee ArrayExpress Genevestigator
MED6 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY