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Human Myocyte-specific enhancer factor 2C (a.a.1-473)
MEF2C Swiss Prot#
Q06413
MEF2C Protein names
Myocyte-specific enhancer factor 2C
MEF2C Gene names
MEF2C
Organism
Human
MEF2C Entry name
MEF2C_HUMAN
MEF2C Codon optimized cDNA Clone
MEF2C CDNA Cat#
RPS0489
cDNA Tag
cDNA MEF2C Contains A 6x histidine tag
Condon optimized MEF2C CDNA Formulation
Liquid
Condon optimized MEF2C CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized MEF2C cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant MEF2C Protein
Recombinant MEF2C Protein Cat#
PS0489
MEF2C Protein Source
Recombinant protein.
Recombinant MEF2C Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant MEF2C Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant MEF2C Protein Activity
N/A
Recombinant protein Tag
Recombinant MEF2C contains A 6x histidine tag
Recombinant MEF2C Protein Formulation
Liquid
Recombinant MEF2C Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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MEF2C Protein family
MEF2 family
MEF2C Subcellular locations
Nucleus.
MEF2C FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Transcription activator which binds specifically to the MEF2

element present in the regulatory regions of many muscle-specific genes.

Controls cardiac morphogenesis and myogenesis, and is also involved in

vascular development. Plays an essential role in hippocampal-dependent

learning and memory by suppressing the number of excitatory synapses and

thus regulating basal and evoked synaptic transmission. Crucial for normal

neuronal development, distribution, and electrical activity in the neocortex.

Necessary for proper development of megakaryocytes and platelets and for

bone marrow B lymphopoiesis. Required for B-cell survival and

proliferation in response to BCR stimulation, efficient IgG1 antibody

responses to T-cell-dependent antigens and for normal induction of germinal

center B cells. May also be involved in neurogenesis and in the

development of cortical architecture (By similarity). Isoform 3 and isoform 4,

which lack the repressor domain, are more active than isoform 1 and

isoform 2.
MEF2C Sequence databases
EMBL DDBJ GenBank
MEF2C 3D structure databases
ModBase
MEF2C Protein-protein interaction databases
STRING
MEF2C Proteomic databases
PRIDE
MEF2C Genome annotation databases
Ensembl GeneID KEGG UCSC
MEF2C Organism specific databases
CTD MGI
MEF2C Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
MEF2C Gene expression databases
Bgee ArrayExpress Genevestigator
MEF2C Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY