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Human N6-adenosine-methyltransferase 70 kDa subunit (a.a.1-580)

METTL3 Swiss Prot#

Q86U44

METTL3 Protein names

N6-adenosine-methyltransferase 70 kDa subunit (MT-A70) (EC 2.1.1.62)

(Methyltransferase-like protein 3)

METTL3 Gene names

METTL3 MTA70

Organism

Human

METTL3 Entry name

MTA70_HUMAN

METTL3 Codon optimized cDNA Clone

METTL3 CDNA Cat#

RPS0497

cDNA Tag

cDNA METTL3 Contains A 6x histidine tag

Condon optimized METTL3 CDNA Formulation

Liquid

Condon optimized METTL3 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized METTL3 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant METTL3 Protein

Recombinant METTL3 Protein Cat#

PS0497

METTL3 Protein Source

Recombinant protein.

Recombinant METTL3 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant METTL3 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant METTL3 Protein Activity

N/A

Recombinant protein Tag

Recombinant METTL3 contains A 6x histidine tag

Recombinant METTL3 Protein Formulation

Liquid

Recombinant METTL3 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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METTL3 Protein family

MT-A70-like family

METTL3 Subcellular locations

Nucleus speckle.

METTL3 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: N6-methyltransferase that methylates adenosine residues of

some mRNAs. N6-methyladenosine (m6A), which is present at internal sites

of some mRNAs, may play a role in the efficiency of mRNA splicing,

transport or translation.

METTL3 Sequence databases

EMBL

DDBJ

GenBank

METTL3 3D structure databases

ModBase

METTL3 Protein-protein interaction databases

STRING

METTL3 Proteomic databases

PRIDE

METTL3 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

METTL3 Organism specific databases

CTD

MGI

METTL3 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

METTL3 Gene expression databases

Bgee

ArrayExpress

Genevestigator

METTL3 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY