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Human Nuclear receptor subfamily 2 group C member 2 (a.a.1-596)
NR2C2 Swiss Prot#
P49116
NR2C2 Protein names
Nuclear receptor subfamily 2 group C member 2 (Orphan nuclear receptor

TR4) (Testicular receptor 4) (Orphan nuclear receptor TAK1)
NR2C2 Gene names
NR2C2 TAK1 TR4
Organism
Human
NR2C2 Entry name
NR2C2_HUMAN
NR2C2 Codon optimized cDNA Clone
NR2C2 CDNA Cat#
RPS0575
cDNA Tag
cDNA NR2C2 Contains A 6x histidine tag
Condon optimized NR2C2 CDNA Formulation
Liquid
Condon optimized NR2C2 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized NR2C2 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant NR2C2 Protein
Recombinant NR2C2 Protein Cat#
PS0575
NR2C2 Protein Source
Recombinant protein.
Recombinant NR2C2 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant NR2C2 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant NR2C2 Protein Activity
N/A
Recombinant protein Tag
Recombinant NR2C2 contains A 6x histidine tag
Recombinant NR2C2 Protein Formulation
Liquid
Recombinant NR2C2 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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NR2C2 Protein family
Nuclear hormone receptor family, NR2 subfamily
NR2C2 Subcellular locations
Nucleus.
NR2C2 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Orphan nuclear receptor that can act as a repressor or

activator of transcription. An important repressor of nuclear recptor

signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3

receptor, thyroid hormone receptor and estrogen receptor pathways. May

regulate gene expression during the late phase of spermatogenesis.

Together with NR2C1, forms the core of the DRED (direct repeat erythroid-

definitive) complex that represses embryonic and fetal globin transcription

including that of GATA1. Binds to hormone response elements (HREs)

consisting of two 5'-AGGTCA-3' half site direct repeat consensus

sequences. Plays a fundamental role in early embryonic development and

embryonic stem cells. Required for normal spermatogenesis and

cerebellum development. Appears to be important for

neurodevelopmentally regulated behavior (By similarity). Activates

transcriptional activity of LHCG. Antagonist of PPARA-mediated

transactivation.
NR2C2 Sequence databases
EMBL DDBJ GenBank
NR2C2 3D structure databases
ModBase
NR2C2 Protein-protein interaction databases
STRING
NR2C2 Proteomic databases
PRIDE
NR2C2 Genome annotation databases
Ensembl GeneID KEGG UCSC
NR2C2 Organism specific databases
CTD MGI
NR2C2 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
NR2C2 Gene expression databases
Bgee ArrayExpress Genevestigator
NR2C2 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY