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Human Pancreas/duodenum homeobox protein 1 (a.a.1-283)
PDX1 Swiss Prot#
P52945
PDX1 Protein names
Pancreas/duodenum homeobox protein 1 (PDX-1) (Insulin promoter factor 1)

(IPF-1) (Islet/duodenum homeobox-1) (IDX-1) (Somatostatin-transactivating

factor 1) (STF-1) (Insulin upstream factor 1) (IUF-1) (Glucose-sensitive factor)

(GSF)
PDX1 Gene names
PDX1 IPF1
Organism
Human
PDX1 Entry name
PDX1_HUMAN
PDX1 Codon optimized cDNA Clone
PDX1 CDNA Cat#
RPS0622
cDNA Tag
cDNA PDX1 Contains A 6x histidine tag
Condon optimized PDX1 CDNA Formulation
Liquid
Condon optimized PDX1 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized PDX1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant PDX1 Protein

Recombinant PDX1 Protein Cat#
PS0622
PDX1 Protein Source
Recombinant protein.
Recombinant PDX1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant PDX1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant PDX1 Protein Activity
N/A
Recombinant protein Tag
Recombinant PDX1 contains A 6x histidine tag
Recombinant PDX1 Protein Formulation
Liquid
Recombinant PDX1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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PDX1 Protein family
Antp homeobox family, IPF1/XlHbox-8 subfamily
PDX1 Subcellular locations
Nucleus.
PDX1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Activates insulin, somatostatin, glucokinase, islet amyloid

polypeptide and glucose transporter type 2 gene transcription. Particularly

involved in glucose-dependent regulation of insulin gene transcription.

Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development,

specifies the early pancreatic epithelium, permitting its proliferation,

branching and subsequent differentiation. At adult stage, required for

maintaining the hormone-producing phenotype of the beta-cell.
PDX1 Sequence databases
EMBL DDBJ GenBank
PDX1 3D structure databases
ModBase
PDX1 Protein-protein interaction databases
STRING
PDX1 Proteomic databases
PRIDE
PDX1 Genome annotation databases
Ensembl GeneID KEGG UCSC
PDX1 Organism specific databases
CTD MGI
PDX1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
PDX1 Gene expression databases
Bgee ArrayExpress Genevestigator
PDX1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY