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Human DNA polymerase epsilon subunit 3 (a.a.1-147)

POLE3 Swiss Prot#

Q9NRF9

POLE3 Protein names

DNA polymerase epsilon subunit 3 (EC 2.7.7.7) (DNA polymerase II subunit

3) (DNA polymerase epsilon subunit p17) (Chromatin accessibility complex

17 kDa protein) (CHRAC-17) (HuCHRAC17) (Arsenic-transactivated protein)

(AsTP)

POLE3 Gene names

POLE3 CHRAC17

Organism

Human

POLE3 Entry name

DPOE3_HUMAN

POLE3 Codon optimized cDNA Clone

POLE3 CDNA Cat#

RPS0641

cDNA Tag

cDNA POLE3 Contains A 6x histidine tag

Condon optimized POLE3 CDNA Formulation

Liquid

Condon optimized POLE3 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized POLE3 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant POLE3 Protein

Recombinant POLE3 Protein Cat#

PS0641

POLE3 Protein Source

Recombinant protein.

Recombinant POLE3 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant POLE3 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant POLE3 Protein Activity

N/A

Recombinant protein Tag

Recombinant POLE3 contains A 6x histidine tag

Recombinant POLE3 Protein Formulation

Liquid

Recombinant POLE3 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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POLE3 Protein family

POLE3 Subcellular locations

Nucleus.

POLE3 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Forms a complex with DNA polymerase epsilon subunit

CHRAC1 and binds naked DNA, which is then incorporated into chromatin,

aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.

POLE3 Sequence databases

EMBL

DDBJ

GenBank

POLE3 3D structure databases

ModBase

POLE3 Protein-protein interaction databases

STRING

POLE3 Proteomic databases

PRIDE

POLE3 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

POLE3 Organism specific databases

CTD

MGI

POLE3 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

POLE3 Gene expression databases

Bgee

ArrayExpress

Genevestigator

POLE3 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY