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Magnetic Separator
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Human REST corepressor 1 (a.a.1-482)
RCOR1 Swiss Prot#
Q9UKL0
RCOR1 Protein names
REST corepressor 1 (Protein CoREST)
RCOR1 Gene names
RCOR1 KIAA0071 RCOR
Organism
Human
RCOR1 Entry name
RCOR1_HUMAN
RCOR1 Codon optimized cDNA Clone
RCOR1 CDNA Cat#
RPS0701
cDNA Tag
cDNA RCOR1 Contains A 6x histidine tag
Condon optimized RCOR1 CDNA Formulation
Liquid
Condon optimized RCOR1 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized RCOR1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant RCOR1 Protein
Recombinant RCOR1 Protein Cat#
PS0701
RCOR1 Protein Source
Recombinant protein.
Recombinant RCOR1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant RCOR1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant RCOR1 Protein Activity
N/A
Recombinant protein Tag
Recombinant RCOR1 contains A 6x histidine tag
Recombinant RCOR1 Protein Formulation
Liquid
Recombinant RCOR1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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RCOR1 Protein family
CoREST family
RCOR1 Subcellular locations
Nucleus.
RCOR1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Essential component of the BHC complex, a corepressor

complex that represses transcription of neuron-specific genes in non-

neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST

and acts by deacetylating and demethylating specific sites on histones,

thereby acting as a chromatin modifier. In the BHC complex, it serves as a

molecular beacon for the recruitment of molecular machinery, including

MeCP2 and SUV39H1, that imposes silencing across a chromosomal

interval. Plays a central role in demethylation of Lys-4 of histone H3 by

promoting demethylase activity of KDM1A on core histones and

nucleosomal substrates. It also protects KDM1A from the proteasome.
RCOR1 Sequence databases
EMBL DDBJ GenBank
RCOR1 3D structure databases
ModBase
RCOR1 Protein-protein interaction databases
STRING
RCOR1 Proteomic databases
PRIDE
RCOR1 Genome annotation databases
Ensembl GeneID KEGG UCSC
RCOR1 Organism specific databases
CTD MGI
RCOR1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
RCOR1 Gene expression databases
Bgee ArrayExpress Genevestigator
RCOR1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY