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Human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member
3 (a.a.1-483)
SMARCD3 Swiss Prot#
Q6STE5
SMARCD3 Protein names
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin

subfamily D member 3 (60 kDa BRG-1/Brm-associated factor subunit C)

(BRG1-associated factor 60C) (BAF60C)
SMARCD3 Gene names
SMARCD3 BAF60C
Organism
Human
SMARCD3 Entry name
SMRD3_HUMAN
SMARCD3 Codon optimized cDNA Clone
SMARCD3 CDNA Cat#
RPS0783
cDNA Tag
cDNA SMARCD3 Contains A 6x histidine tag
Condon optimized SMARCD3 CDNA Formulation
Liquid
Condon optimized SMARCD3 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized SMARCD3 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant SMARCD3 Protein
Recombinant SMARCD3 Protein Cat#
PS0783
SMARCD3 Protein Source
Recombinant protein.
Recombinant SMARCD3 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant SMARCD3 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant SMARCD3 Protein Activity
N/A
Recombinant protein Tag
Recombinant SMARCD3 contains A 6x histidine tag
Recombinant SMARCD3 Protein Formulation
Liquid
Recombinant SMARCD3 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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SMARCD3 Protein family
SMARCD family
SMARCD3 Subcellular locations
Nucleus.
SMARCD3 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Plays a role in ATP dependent nucleosome remodeling by

SMARCA4 containing complexes. Stimulates nuclear receptor mediated

transcription. Belongs to the neural progenitors-specific chromatin

remodeling complex (npBAF complex) and the neuron-specific chromatin

remodeling complex (nBAF complex). During neural development a switch

from a stem/progenitor to a post-mitotic chromatin remodeling mechanism

occurs as neurons exit the cell cycle and become committed to their adult

state. The transition from proliferating neural stem/progenitor cells to post-

mitotic neurons requires a switch in subunit composition of the npBAF and

nBAF complexes. As neural progenitors exit mitosis and differentiate into

neurons, npBAF complexes which contain ACTL6A/BAF53A and

PHF10/BAF45A, are exchanged for homologous alternative

ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-

specific complexes (nBAF). The npBAF complex is essential for the self-

renewal/proliferative capacity of the multipotent neural stem cells. The nBAF

complex along with CREST plays a role regulating the activity of genes

essential for dendrite growth (By similarity).
SMARCD3 Sequence databases
EMBL DDBJ GenBank
SMARCD3 3D structure databases
ModBase
SMARCD3 Protein-protein interaction databases
STRING
SMARCD3 Proteomic databases
PRIDE
SMARCD3 Genome annotation databases
Ensembl GeneID KEGG UCSC
SMARCD3 Organism specific databases
CTD MGI
SMARCD3 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
SMARCD3 Gene expression databases
Bgee ArrayExpress Genevestigator
SMARCD3 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY