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Bio-Magnetic Purification
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Magnetic Separator
Magnetic Beads and Applications
Affinity Magnetic Beads
  • Amine-d
  • Aldehyde
  • Carboxyl-d
  • CDI-activated
  • DVS
  • DADPA-d
  • Epoxy
  • Hydrazide-d
  • Hydroxyl-d
  • Iodoacetyl
  • NHS
  • Sulfhydryl-d
  • Tosyl
  • Thiol
  • Silica
  • IDA-modified
Reversed-Phase  Beads
  • C4
  • C8
  • C18
  • Cyanopropyl
  • Phenyl
  • diPhenyl
Ion Exchange Beads
  • DEAE (WAX)
  • PSA (WAX)
  • SAX
  • WCX
  • SCX
  • Hydroxyapatite
Antibody Purification & IP
  • Protein A
  • Protein G
  • Protein A/G
  • Protein L
  • Quick IgG Pure Beads
  • Antigen Peptide
  • Quick IgM Pure Beads
  • Anti-IgG Beads
  • Quick IgA Pure Bead
  • Thiophillic Beads
Antibody Immobilization
  • Protein A
  • Protein G
  • Protein A/G
  • Protein L
  • Epoxy
  • Aldehyde
  • Hydrazide-d
  • Carboxyl-d
  • Iodoacetyl
  • Thiol
Recombinant Protein
Purification
  • Ni+ Charged Beads
  • Co+ Charged Beads
  • Maltose
  • Calmodulin Beads
Peptide Immobilization
  • Epoxy
  • Aldehyde
  • Carboxyl-d
  • Amine-d
  • Iodoacetyl
  • Thiol
DNA/RNA Purification
  • Blood
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  • Soil
  • PCR Products
  • mRNA
  • Heteroduplex DNA
    (Mutation Isolation)
DNA/RNA Immobilization
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Endotoxin Removal
Small Molecule
Immobilization
Carbohydrate
Immobilization
  • Epoxy
  • Aldehyde
  • Hydrazide-d
  • DVS
Abundant Protein Removal
  • HSA Removal
  • IgG Removal
  • HSA/IgG Removal
  • Abundant-10 Protein
  • Abundant-22 Protein
 
Cell Isolation
  • Virus
  • Bacteria
  • Cell
  • Parasites
EDTA-Magnetic BEads
Miscellaneous
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  • Enzyme
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  • Peptide
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IDA-Magnetic Beads
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  • For cDNA or Recombinant Protein Search ( Input Cat#,
    or Gene name, or Protein Name, or Accession Number
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Human Autoimmune regulator (a.a.1-545)
AIRE Swiss Prot#
O43918
AIRE Protein names
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis

ectodermal dystrophy protein) (APECED protein)
AIRE Gene names
AIRE APECED
Organism
Human
AIRE Entry name
AIRE_HUMAN
AIRE Codon optimized cDNA Clone
AIRE CDNA Cat#
RPS0008
cDNA Tag
cDNA AIRE Contains A 6x histidine tag
Condon optimized AIRE CDNA Formulation
Liquid
Condon optimized AIRE CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized AIRE cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant AIRE Protein

Recombinant AIRE Protein Cat#
PS0008
AIRE Protein Source
Recombinant protein.
Recombinant AIRE Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant AIRE Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant AIRE Protein Activity
N/A
Recombinant protein Tag
Recombinant AIRE contains A 6x histidine tag
Recombinant AIRE Protein Formulation
Liquid
Recombinant AIRE Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Place Order for Recombinant AIRE Protein or cDNA
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AIRE Protein family
-
AIRE Subcellular locations
Nucleus. Cytoplasm.
AIRE FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Transcriptional regulator that binds to DNA as a dimer or as a

tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich

environment; the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3'

combined with a 5'-TTATTA-3' box. Binds to nucleosomes (By similarity).

Binds to chromatin and interacts selectively with histone H3 that is not

methylated at 'Lys-4', not phosphorylated at 'Thr-3' and not methylated at

'Arg-2'. Functions as a sensor of histone H3 modifications that are important

for the epigenetic regulation of gene expression. Functions as a

transcriptional activator and promotes the expression of otherwise tissue-

specific self-antigens in the thymus, which is important for self tolerance

and the avoidance of autoimmune reactions.
AIRE Sequence databases
EMBL DDBJ GenBank
AIRE 3D structure databases
ModBase
AIRE Protein-protein interaction databases
STRING
AIRE Proteomic databases
PRIDE
AIRE Genome annotation databases
Ensembl GeneID KEGG UCSC
AIRE Organism specific databases
CTD MGI
AIRE Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
AIRE Gene expression databases
Bgee ArrayExpress Genevestigator
AIRE Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY