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Human TAR DNA-binding protein 43 (a.a.1-414)
TARDBP Swiss Prot#
Q13148
TARDBP Protein names
TAR DNA-binding protein 43 (TDP-43)
TARDBP Gene names
TARDBP TDP43
Organism
Human
TARDBP Entry name
TADBP_HUMAN
TARDBP Codon optimized cDNA Clone
TARDBP CDNA Cat#
RPS0854
cDNA Tag
cDNA TARDBP Contains A 6x histidine tag
Condon optimized TARDBP CDNA Formulation
Liquid
Condon optimized TARDBP CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized TARDBP cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TARDBP Protein
Recombinant TARDBP Protein Cat#
PS0854
TARDBP Protein Source
Recombinant protein.
Recombinant TARDBP Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant TARDBP Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant TARDBP Protein Activity
N/A
Recombinant protein Tag
Recombinant TARDBP contains A 6x histidine tag
Recombinant TARDBP Protein Formulation
Liquid
Recombinant TARDBP Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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TARDBP Protein family
-
TARDBP Subcellular locations
Nucleus.
TARDBP FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: DNA and RNA-binding protein which regulates transcription and

splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon

9 skipping by binding to the UG repeated motifs in the polymorphic region

near the 3'-splice site of this exon. The resulting aberrant splicing is

associated with pathological features typical of cystic fibrosis. May also be

involved in microRNA biogenesis, apoptosis and cell division. Can repress

HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes

the low molecular weight neurofilament (NFL) mRNA through a direct

interaction with the 3' UTR.
TARDBP Sequence databases
EMBL DDBJ GenBank
TARDBP 3D structure databases
ModBase
TARDBP Protein-protein interaction databases
STRING
TARDBP Proteomic databases
PRIDE
TARDBP Genome annotation databases
Ensembl GeneID KEGG UCSC
TARDBP Organism specific databases
CTD MGI
TARDBP Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
TARDBP Gene expression databases
Bgee ArrayExpress Genevestigator
TARDBP Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY