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Human Transcriptional enhancer factor TEF-1 (a.a.1-426)
TEAD1 Swiss Prot#
P28347
TEAD1 Protein names
Transcriptional enhancer factor TEF-1 (TEA domain family member 1) (TEAD-

1) (Protein GT-IIC) (Transcription factor 13) (TCF-13) (NTEF-1)
TEAD1 Gene names
TEAD1 TCF13 TEF1
Organism
Human
TEAD1 Entry name
TEAD1_HUMAN
TEAD1 Codon optimized cDNA Clone
TEAD1 CDNA Cat#
RPS0884
cDNA Tag
cDNA TEAD1 Contains A 6x histidine tag
Condon optimized TEAD1 CDNA Formulation
Liquid
Condon optimized TEAD1 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized TEAD1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TEAD1 Protein
Recombinant TEAD1 Protein Cat#
PS0884
TEAD1 Protein Source
Recombinant protein.
Recombinant TEAD1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant TEAD1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant TEAD1 Protein Activity
N/A
Recombinant protein Tag
Recombinant TEAD1 contains A 6x histidine tag
Recombinant TEAD1 Protein Formulation
Liquid
Recombinant TEAD1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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TEAD1 Protein family
-
TEAD1 Subcellular locations
Nucleus.
TEAD1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Transcription factor which plays a key role in the Hippo signaling

pathway, a pathway involved in organ size control and tumor suppression

by restricting proliferation and promoting apoptosis. The core of this pathway

is composed of a kinase cascade wherein MST1/MST2, in complex with its

regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex

with its regulatory protein MOB1, which in turn phosphorylates and

inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene

expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation,

migration and epithelial mesenchymal transition (EMT) induction. Binds

specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-

GTGGAATGT-3') and activates transcription in vivo in a cell-specific

manner. The activation function appears to be mediated by a limiting cell-

specific transcriptional intermediary factor (TIF). Involved in cardiac

development. Binds to the M-CAT motif.
TEAD1 Sequence databases
EMBL DDBJ GenBank
TEAD1 3D structure databases
ModBase
TEAD1 Protein-protein interaction databases
STRING
TEAD1 Proteomic databases
PRIDE
TEAD1 Genome annotation databases
Ensembl GeneID KEGG UCSC
TEAD1 Organism specific databases
CTD MGI
TEAD1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
TEAD1 Gene expression databases
Bgee ArrayExpress Genevestigator
TEAD1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY