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Human Transcription factor A, mitochondrial (a.a.1-246)
TFAM Swiss Prot#
Q00059
TFAM Protein names
Transcription factor A, mitochondrial (mtTFA) (Mitochondrial transcription

factor 1) (MtTF1) (Transcription factor 6) (TCF-6) (Transcription factor 6-like 2)
TFAM Gene names
TFAM TCF6 TCF6L2
Organism
Human
TFAM Entry name
TFAM_HUMAN
TFAM Codon optimized cDNA Clone
TFAM CDNA Cat#
RPS0889
cDNA Tag
cDNA TFAM Contains A 6x histidine tag
Condon optimized TFAM CDNA Formulation
Liquid
Condon optimized TFAM CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized TFAM cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TFAM Protein
Recombinant TFAM Protein Cat#
PS0889
TFAM Protein Source
Recombinant protein.
Recombinant TFAM Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant TFAM Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant TFAM Protein Activity
N/A
Recombinant protein Tag
Recombinant TFAM contains A 6x histidine tag
Recombinant TFAM Protein Formulation
Liquid
Recombinant TFAM Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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TFAM Protein family
-
TFAM Subcellular locations
Mitochondrion.
TFAM FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Binds to the mitochondrial light strand promoter and functions in

mitochondrial transcription regulation. Required for accurate and efficient

promoter recognition by the mitochondrial RNA polymerase. Promotes

transcription initiation from the HSP1 and the light strand promoter by

binding immediately upstream of transcriptional start sites. Is able to unwind

and bend DNA. Required for maintenance of normal levels of mitochondrial

DNA. May play a role in organizing and compacting mitochondrial DNA.

target DNA. Interacts with TFB1M and TFB2M.
TFAM Sequence databases
EMBL DDBJ GenBank
TFAM 3D structure databases
ModBase
TFAM Protein-protein interaction databases
STRING
TFAM Proteomic databases
PRIDE
TFAM Genome annotation databases
Ensembl GeneID KEGG UCSC
TFAM Organism specific databases
CTD MGI
TFAM Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
TFAM Gene expression databases
Bgee ArrayExpress Genevestigator
TFAM Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY