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Human Dimethyladenosine transferase 2, mitochondrial (a.a.1-396)

TFB2M Swiss Prot#

Q9H5Q4

TFB2M Protein names

Dimethyladenosine transferase 2, mitochondrial (EC 2.1.1.-) (S-

adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2)

(Mitochondrial 12S rRNA dimethylase 2) (Mitochondrial transcription factor

B2) (mtTFB2) (h-mtTFB2) (h-mtTFB) (hTFB2M) (Hepatit

TFB2M Gene names

TFB2M NS5ATP5

Organism

Human

TFB2M Entry name

TFB2M_HUMAN

TFB2M Codon optimized cDNA Clone

TFB2M CDNA Cat#

RPS0897

cDNA Tag

cDNA TFB2M Contains A 6x histidine tag

Condon optimized TFB2M CDNA Formulation

Liquid

Condon optimized TFB2M CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized TFB2M cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TFB2M Protein

Recombinant TFB2M Protein Cat#

PS0897

TFB2M Protein Source

Recombinant protein.

Recombinant TFB2M Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant TFB2M Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant TFB2M Protein Activity

N/A

Recombinant protein Tag

Recombinant TFB2M contains A 6x histidine tag

Recombinant TFB2M Protein Formulation

Liquid

Recombinant TFB2M Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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TFB2M Protein family

Methyltransferase superfamily, rRNA adenine N(6)-methyltransferase family,

KsgA subfamily

TFB2M Subcellular locations

Mitochondrion.

TFB2M FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: S-adenosyl-L-methionine-dependent methyltransferase which

specifically dimethylates mitochondrial 12S rRNA at the conserved stem

loop. Also required for basal transcription of mitochondrial DNA, probably

via its interaction with POLRMT and TFAM. Stimulates transcription

independently of the methyltransferase activity. Compared to TFB1M, it

activates transcription of mitochondrial DNA more efficiently, while it has

less methyltransferase activity.

TFB2M Sequence databases

EMBL

DDBJ

GenBank

TFB2M 3D structure databases

ModBase

TFB2M Protein-protein interaction databases

STRING

TFB2M Proteomic databases

PRIDE

TFB2M Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

TFB2M Organism specific databases

CTD

MGI

TFB2M Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

TFB2M Gene expression databases

Bgee

ArrayExpress

Genevestigator

TFB2M Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY