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Human Carbohydrate sulfotransferase 14 (a.a.1-376)
CHST14 Swiss Prot#
Q8NCH0
CHST14 Protein names
Carbohydrate sulfotransferase 14 (EC 2.8.2.-) (Dermatan 4-sulfotransferase

1) (D4ST-1) (hD4ST1)
CHST14 Gene names
CHST14 D4ST1 UNQ1925/PRO4400
Organism
Human
CHST14 Entry name
CHSTE_HUMAN
CHST14 Codon optimized cDNA Clone
CHST14 CDNA Cat#
RPS0090
cDNA Tag
cDNA CHST14 Contains A 6x histidine tag
Condon optimized CHST14 CDNA Formulation
Liquid
Condon optimized CHST14 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized CHST14 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant CHST14 Protein
Recombinant CHST14 Protein Cat#
PS0090
CHST14 Protein Source
Recombinant protein.
Recombinant CHST14 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CHST14 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CHST14 Protein Activity
N/A
Recombinant protein Tag
Recombinant CHST14 contains A 6x histidine tag
Recombinant CHST14 Protein Formulation
Liquid
Recombinant CHST14 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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CHST14 Protein family
Sulfotransferase 2 family
CHST14 Subcellular locations
Golgi apparatus membrane; Single-pass type II membrane protein.
CHST14 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Catalyzes the transfer of sulfate to position 4 of the N-

acetylgalactosamine (GalNAc) residue of dermatan sulfate. Transfers sulfate

to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an

alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate

more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-

GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan

sulfate. Addition of sulfate to GalNAc may occur immediately after

epimerization of GlcUA to IdoUA.
CHST14 Sequence databases
EMBL DDBJ GenBank
CHST14 3D structure databases
ModBase
CHST14 Protein-protein interaction databases
STRING
CHST14 Proteomic databases
PRIDE
CHST14 Genome annotation databases
Ensembl GeneID KEGG UCSC
CHST14 Organism specific databases
CTD MGI
CHST14 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CHST14 Gene expression databases
Bgee ArrayExpress Genevestigator
CHST14 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY