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Human Transforming growth factor beta-1-induced transcript 1 protein (a.a.1-461)
TGFB1I1 Swiss Prot#
O43294
TGFB1I1 Protein names
Transforming growth factor beta-1-induced transcript 1 protein (Hydrogen

peroxide-inducible clone 5 protein) (Hic-5) (Androgen receptor-associated

protein of 55 kDa) (Androgen receptor coactivator 55 kDa protein)
TGFB1I1 Gene names
TGFB1I1 ARA55
Organism
Human
TGFB1I1 Entry name
TGFI1_HUMAN
TGFB1I1 Codon optimized cDNA Clone
TGFB1I1 CDNA Cat#
RPS0907
cDNA Tag
cDNA TGFB1I1 Contains A 6x histidine tag
Condon optimized TGFB1I1 CDNA Formulation
Liquid
Condon optimized TGFB1I1 CDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
Condon optimized TGFB1I1 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant TGFB1I1 Protein
Recombinant TGFB1I1 Protein Cat#
PS0907
TGFB1I1 Protein Source
Recombinant protein.
Recombinant TGFB1I1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant TGFB1I1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant TGFB1I1 Protein Activity
N/A
Recombinant protein Tag
Recombinant TGFB1I1 contains A 6x histidine tag
Recombinant TGFB1I1 Protein Formulation
Liquid
Recombinant TGFB1I1 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw
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TGFB1I1 Protein family
Paxillin family
TGFB1I1 Subcellular locations
Cell junction > focal adhesion. Nucleus matrix. Cytoplasm > cytoskeleton.
TGFB1I1 FUNCTION (According to UniProtKB/Swiss Prot)
FUNCTION: Functions as a molecular adapter coordinating multiple protein-

protein interactions at the focal adhesion complex and in the nucleus. Links

various intracellular signaling modules to plasma membrane receptors and

regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3

and SLC6A4 targeting to the plasma membrane hence regulating their

activity. In the nucleus, functions as a nuclear receptor coactivator

regulating glucocorticoid, androgen, mineralocorticoid and progesterone

receptor transcriptional activity. May play a role in the processes of cell

growth, proliferation, migration, differentiation and senescence. May have a

zinc-dependent DNA-binding activity.
TGFB1I1 Sequence databases
EMBL DDBJ GenBank
TGFB1I1 3D structure databases
ModBase
TGFB1I1 Protein-protein interaction databases
STRING
TGFB1I1 Proteomic databases
PRIDE
TGFB1I1 Genome annotation databases
Ensembl GeneID KEGG UCSC
TGFB1I1 Organism specific databases
CTD MGI
TGFB1I1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
TGFB1I1 Gene expression databases
Bgee ArrayExpress Genevestigator
TGFB1I1 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY