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Human Potassium voltage-gated channel subfamily H member 2 (a.a.660–1159)

KCNH2 Swiss Prot#

Q12809

KCNH2 Protein names

Potassium voltage-gated channel subfamily H member 2 (Voltage-gated

potassium channel subunit Kv11.1) (Ether-a-go-go-related gene potassium

channel 1) (Ether-a-go-go-related protein 1) (Eag-related protein 1) (ERG-1)

(hERG-1) (hERG1) (H-ERG) (Eag homolog)

KCNH2 Gene names

KCNH2 (ERG) (ERG1) (HERG)

Organism

Human

KCNH2 Entry name

Plexin domain-containing protein 1 (Tumor endothelial marker 7)

KCNH2 Codon optimized cDNA Clone

KCNH2 CDNA Cat#

RPE0784

cDNA Tag

cDNA KCNH2 Contains A 6x histidine tag

Condon optimized KCNH2 CDNA Formulation

Liquid

Condon optimized KCNH2 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized KCNH2 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant KCNH2 Protein

Recombinant KCNH2 Protein Cat#

PE0784

KCNH2 Protein Source

Recombinant protein.

Recombinant KCNH2 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant KCNH2 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant KCNH2 Protein Activity

N/A

Recombinant protein Tag

Recombinant KCNH2 contains A 6x histidine tag

Recombinant KCNH2 Protein Formulation

Liquid

Recombinant KCNH2 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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KCNH2 Protein family

Potassium channel family, H (Eag) (TC 1.A.1.20) subfamily, Kv11.1/KCNH2

sub-subfamily

KCNH2 Subcellular locations

Membrane; Multi-pass membrane protein.

KCNH2 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying

potassium channel. Channel properties are modulated by cAMP and subunit

assembly. Mediates the rapidly activating component of the delayed

rectifying potassium current in heart (IKr). Isoform 3 has no channel activity

by itself, but modulates channel characteristics when associated with

isoform 1.

KCNH2 Sequence databases

EMBL

DDBJ

GenBank

KCNH2 3D structure databases

ModBase

KCNH2 Protein-protein interaction databases

STRING

KCNH2 Proteomic databases

PRIDE

KCNH2 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

KCNH2 Organism specific databases

CTD

MGI

KCNH2 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

KCNH2 Gene expression databases

Bgee

ArrayExpress

Genevestigator

KCNH2 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY